d. Zone of calcified cartilage ο only a few cells thick, ο ο only a few cells thick, ο Zone of resting/ reserve cartilage Zone of proliferation Zone of hypertrophy Zone of ossification Zone of calcification bone . EXTRACELLULAR MATRIX OF BONE OSTEOID - MIXTURE OF TYPE I COLLAGEN AND COMPLEX MATRIX MATERIAL TO INCREASE THE AFFINITY AND SERVE AS NUCLEATION SITES Blood vessel invasion was almost completely suppressed, concomitant with impaired trabecular bone formation and expansion of hypertrophic chondrocyte zone. Zone of hypertrophic cartilage A. Chondrocytes stop dividing and start to hypotrophy (enlarge). Minerals deposited in the matrix between lacunae columns. Articular Cartilage Progenitor Cells. only a few cells thick and consists mostly of chondrocytes thst are dead because the ECM around them has calcified. .hypertrophied chondrocytes dying or lysed away, matrix material calcified, invasion of capillaries osteogenic cells. Describe the zone of resting cartilage in the epiphyseal plate? hyaline cartilage anchors growth plate to bone. As cartilage grows, the entire structure grows in length and then is turned into bone. Zone of calcified cartilage A. 4. B. Lacunae walls become thin as the chondrocytes resorb matrix during hypotrophy. this layer consists of large, maturing chondrocytes arranged in columns. Once cartilage cannot grow further, the structure cannot elongate more. 3. Zone of hypertrophic cartilage. This preview shows page 121 - 125 out of 225 pages.. c. Zone of Hypertrophic cartilage ο extremely large chrondrocytes that are arranged in columns, ο maturing cells. 3. Articular cartilage progenitor cells (ACPCs) usually exist in one third of the superficial zone of articular cartilage. Metaphyseal (osteogenic) zone . 4. Zone of maturing cartilage . 3. Zone of Calcified Cartilage Zone of Hypertrophic Cartilage a. Layer consists of cells that are getting larger and are still shaped like stacked coins 4. . On the diaphyseal side of the growth plate, cartilage calcifies and dies, then is replaced by bone (figure 6.43, zones of hypertrophy and maturation, calcification and ossification). Narrow zone of cartilage only a few cells thick B. . 5. Zone of calcified cartilage. cell division ceases, chondrocytes increase in size. Articular cartilage can be divided into four zones depending on the collagen and proteoglycan organization and content: the superficial zone, the transitional zone, the middle (radial) or deep zone, and the calcified cartilage zone (Fig. (calcification kills chondrocytes and matrix appears opaque). . 1)zone of reserve cartilage, 2)proliferation, 3)maturation, 4)hypertrophy, 5)degeneration, 6)ossification Definition list the zones in the epiphyseal plate (6-in order epiphysis to diaphysis) Zone of hypertrophy and calcification . 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